Two forensic case reports attributed deaths to acute yohimbine intoxication after high blood concentrations were measured. These reports show possible severe toxicity; they do not quantify risk at ordinary exposures.[1]
- Forensic cases without an exposed-population denominator; no safe threshold established.
- Abstract-checked; no qualified clinical review.
Inspection history
Clinical review: not reviewed by a qualified clinician.
· Independent source inspection; applicability narrowed and inherited assertions excluded where unsupported. No qualified clinical review.
· Independently reopened the PubMed abstract via NCBI E-utilities. Confirmed exactly: two cases, blood yohimbine 7,400 and 5,400 ng/mL (reported therapeutic range 40-400 ng/mL; overdose neurotoxic effects reported up to 5,000 ng/mL); medical examiners in both cases determined cause of death as acute yohimbine intoxication, manner accident. Attempted the Oxford Academic publisher page (access-gated, HTTP 403) and confirmed via Europe PMC this record is not open access; full text remains unobtained. No correction needed to the claim text; no qualified clinical review.